Richard Knox

Since he joined NPR in 2000, Knox has covered a broad range of issues and events in public health, medicine, and science. His reports can be heard on NPR's Morning Edition, All Things Considered, Weekend Edition, Talk of the Nation, and newscasts.

Among other things, Knox's NPR reports have examined the impact of HIV/AIDS in Africa, North America, and the Caribbean; anthrax terrorism; smallpox and other bioterrorism preparedness issues; the rising cost of medical care; early detection of lung cancer; community caregiving; music and the brain; and the SARS epidemic.

Before joining NPR, Knox covered medicine and health for The Boston Globe. His award-winning 1995 articles on medical errors are considered landmarks in the national movement to prevent medical mistakes. Knox is a graduate of the University of Illinois and Columbia University. He has held yearlong fellowships at Stanford and Harvard Universities, and is the author of a 1993 book on Germany's health care system.

He and his wife Jean, an editor, live in Boston. They have two daughters.

A smoldering epidemic already affects an estimated 4 million Americans, most of whom don't know it.

It's hepatitis C, an insidious virus that can hide in the body for two or three decades without causing symptoms — and then wreak havoc with the liver, scarring it so extensively that it can fail. Half of all people waiting for liver transplants have hepatitis C.

Not quite 10 months after Haiti's devastating 2010 earthquake, a more insidious disaster struck: cholera.

Haiti hadn't seen cholera for at least a century. Then suddenly, the first cases appeared in the central highlands near a camp for United Nations peacekeeping forces.

It's no news that the U.S. has lower life expectancy and higher infant mortality than most high-income countries. But a magisterial new report says Americans are actually less healthy across their entire life spans than citizens of 16 other wealthy nations.

And the gap is steadily widening.

The past year has seen more debate about the best way to find breast cancers.

A recent analysis concluded that regular mammograms haven't reduced the rate of advanced breast cancers — but they have led more than a million women to be diagnosed with tumors that didn't need to be treated.

Niacin, a B vitamin that raises "good" cholesterol, has failed to benefit heart disease patients when taken in tandem with a statin drug that lowers "bad" cholesterol, according to drug maker Merck.

Opportunists who market street drugs may be undermining the global struggle against AIDS.

In South Africa, two mainstay HIV drugs have found their way into recreational use. That may help explain why some HIV patients are resistant to these front-line medicines even if they've never been in treatment before.

It can happen in two ways.

Boston brain surgeon Ed Smith points to a tangle of delicate gray shadows on his computer screen. It's an X-ray of the blood vessels on the left side of 13-year-old Maribel Ramos' brain.

The World Health Organization says a new coronavirus has killed two people in Jordan — the third country where the novel microbe has been traced.

That brings lab-confirmed cases to nine, with five fatalities.

Before Secretary of State Hilary Rodham Clinton passes the reins to her successor, she's got a few loose ends to tie up. One of them is mapping out the U.S.'s continuing efforts to combat AIDS around the world.

So today she unveiled a "blueprint" for what she called an "AIDS-free generation."

Now Clinton isn't talking about ending the HIV pandemic altogether. Rather, she hopes to prevent most new infections from occurring in the first place and to stop HIV-positive people from developing AIDS.

It's a startling trend: Many women with cancer in one breast are choosing to have their healthy breast removed, too.

But a study being presented later this week says more than three-quarters of women who opt for double mastectomies are not getting any benefit because their risk of cancer developing in the healthy breast is no greater than in women without cancer.

The endless debate over routine mammograms is getting another kick from an analysis that sharply questions whether the test really does what it's supposed to.

Dr. H. Gilbert Welch, coauthor of the analysis of mammography's impact, which was just published in The New England Journal of Medicine, tell Shots that the aim was to "get down to a very basic question."

The public health world has waited for the results for more than a year. After a half-billion dollars in R&D, would the front-runner malaria vaccine protect the top-priority targets: young infants?

The results are disappointing. The vaccine — called RTS,S for its various molecular components — reduced infants' risk of malaria by about a third.

One lasting image of Superstorm Sandy will be very sick patients being evacuated from flooded hospitals. But less visible are thousands of patients who rely on visiting nurses and home health aides for care ranging from bathing and feeding to oxygen and ventilators.

Hurricane Sandy only sideswiped Haiti during its early days. But reports so far suggest that even this indirect hit led to nearly as many deaths there as in the U.S. after the storm made landfall on the Mid-Atlantic coast.

As of Wednesday, Haiti had documented 54 deaths caused by Sandy — most in the nation's southern peninsula, which points toward Jamaica. Another 21 Haitians were still counted as missing, and many fear the death toll will rise as officials reach affected areas isolated by impassable roads and ruined bridges.

In a highly unusual step, the Food and Drug Administration has released a report of inspections it conduct this month of the Massachusetts pharmacy at the center of a national outbreak of fungal infections.

Two weeks after Matthew Spencer got a spinal injection for his chronic back pain, he felt "not quite right." Nothing too specific: worsening headache, nausea.

Then he saw a TV report on a recall of contaminated steroid medication used for back pain.

"I thought, well, I don't know if I had that medicine or not, but maybe I'd better go check it out," Spencer says.

As the caseload of fungal meningitis linked to a tainted steroid drug climbs, experts are learning more about this human-made epidemic. The signs indicate that cases could still be emerging until Thanksgiving or beyond.

The latest count is 268 cases of meningitis and three patients with fungal joint infections, spread across 16 states from New Hampshire to Texas and Idaho to Florida. Twenty-one people have died.

A small study offers a bit of cautious optimism about the prospects for treatment of tuberculosis, one of humankind's most ancient scourges.

This week's New England Journal of Medicine has a report showing that adding a 12-year-old antibiotic called linezolid, brand name Zyvox, to existing treatments cured nearly 90 percent of patients with a form of tuberculosis resistant to both first- and second-line antibiotics.

There's new information on the ongoing outbreak of a rare meningitis caused by a fungus that somehow got into a steroid drug. Federal officials now say the drug got injected into 14,000 patients — 1,000 more than earlier thought.

The government has named 75 medical facilities that received a potentially contaminated drug suspected of infecting 47 patients with meningitis nationwide.

It now appears that the new coronavirus found on the Arabian Peninsula is more widespread than initially thought, even though only two people are known to have gotten sick from it.

At first it seemed likely that the two known cases of illness from the new cousin-of-SARS virus may have been exposed in or near the Saudi Arabian city of Jeddah on the Red Sea coast.

It's a troubling story authorities think will unfold over the next month or so. An untold number of Americans who got steroid injections in their spine to relieve back pain may end up with a rare fungal meningitis. The drug was contaminated with the spores of a common leaf mold — nobody knows how.

So far, the Centers for Disease Control and Prevention has recorded 35 cases of the fungal meningitis in six states: Tennessee, North Carolina, Florida, Virginia, Maryland and Indiana. Five patients have died.

Scientists have recently discovered three new human viruses.

Should you take Vitamin D supplements to prevent colds and shorten the misery?

Like other theories about the benefits of vitamin D, it seems like a reasonably good idea. After all, some lab studies suggest vitamin D might enhance immunity. And as everybody knows, people are more prone to respiratory infections during winter, when they cover up and get less vitamin D-generating sunlight.

New viruses are popping up all over these days – Heartland virus in Missouri last month, a new virus in the same family as SARS in Saudi Arabia this month. And now, a never-before-seen hemorrhagic fever virus in central Africa.

Brief counseling from primary care doctors reduces "risky" drinking, defined as having more than four drinks a day for men, three for women, a federal task force says.

About one in three Americans misuse alcohol, the panel says, with the vast majority falling in the "risky" category.

Scientists have known for a while that breast cancer is really four different diseases, with subtypes among them, an insight that has helped improve treatment for some women.

But experts haven't understood much about how these four types differ. A new report, published online in the journal Nature, provides a big leap in that understanding.

A Swedish medical team has transplanted uteruses from two women in their 50s to their daughters. Meanwhile, Shots has learned that an Indiana group is recruiting women willing to undergo womb transplants in this country.

"We could go ahead tomorrow if we found the perfect candidate," Dr. Giuseppe Del Priore told Shots.

A lot of medicine's direst emergencies come down to one problem: lack of oxygen.

Cardiologist John Kheir started thinking about that when a little girl in his care, drowning from lung hemorrhages, died before she could be hooked up to a heart-lung machine that would have kept her blood oxygenated while the damage was repaired.

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